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T60075 |
Dopamine D2 receptor agonist-2
|
Dopamine D2 Receptor |
Dopamine Receptor
|
|
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor. |
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T11077 |
Dopamine D2 receptor antagonist-1
|
|
Others
|
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Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity. |
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T7635 |
Raclopride
|
|
Dopamine Receptor
|
|
Raclopride is a selective antagonist of dopamine D2/D3 receptor. |
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T4007 |
Eticlopride hydrochloride
|
|
Dopamine Receptor
|
|
Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM). |
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T16392 |
ONC206
|
|
Dopamine Receptor
|
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ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and possesses broad-spectrum anti-tumor activity. |
|
TQ0084 |
Lumateperone Tosylate
|
ITI-007 |
Dopamine Receptor
,
5-HT Receptor
|
|
lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki: 32 nM). |
|
T0280 |
Spiperone
|
Spiroperidol,Spiropitan |
Dopamine Receptor
|
|
Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA. |
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T21069 |
Lumateperone
|
ITI 722,ITI722,ITI-007,ITI007 |
5-HT Receptor
|
|
Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM). |
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T7943 |
Fluphenazine decanoate
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|
Dopamine Receptor
|
|
Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. |
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T2226 |
Pergolide mesylate
|
Pergolide mesylate salt,LY127809,Pergolide methanesulfonate |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES. |
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T8136 |
Perospirone hydrochloride
|
Perospirone HCl,SM-9018 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
|
|
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist. |
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T10683 |
Carmoxirole hydrochloride
|
EMD 45609 hydrochloride |
Dopamine Receptor
|
|
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo. |
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T3497 |
Ocaperidone
|
Ocaperidona,R79598 |
Dopamine Receptor
,
5-HT Receptor
|
|
Ocaperidona (Ocaperidone (Ocaperidona)), a very high affinity dopamine D2 antagonist. |
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T9228 |
Propionylpromazine hydrochloride
|
Propiopromazine hydrochloride |
Dopamine Receptor
|
|
Propionylpromazine hydrochloride (Propiopromazine hydrochloride) is a dopamine receptor D2 (DRD2) antagonist. |
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T70302 |
Fallypride
|
|
Dopamine Receptor
|
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Fallypride is a potent and selective dopamine D2/D3 receptor antagonist. |
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T7180 |
Sultopride hydrochloride
|
LIN-1418 hydrochloride |
Dopamine Receptor
|
|
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective dopamine D2 and D3 receptor antagonist. |
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T22817 |
GSK 789472 hydrochloride
|
GSK-789472 HCl,1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one hydrochloride,4,5-Dihydro-1-phenyl-3-(2-piperidinyl)methylimidazol-2(1H)-one |
Dopamine Receptor
|
|
GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist. |
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T0302 |
Triflupromazine hydrochloride
|
Neoprin,Fluopromazine hydrochloride,Fluorofen,Flumazin |
Dopamine Receptor
,
5-HT Receptor
,
AChR
,
Autophagy
|
|
Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists. |
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T6142 |
PD128907 HCl
|
|
Dopamine Receptor
|
|
PD128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor. |
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T30098 |
Aplindore Fumarate
|
Aplindore,DAB-452 Fumarate,DAB-452 |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-H... |
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T14083 |
Abaperidone
|
|
Dopamine Receptor
,
5-HT Receptor
|
|
Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperidone is a potentially atypical anti-psychotropic compound th... |
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T3187 |
Fluoroclebopride
|
|
Dopamine Receptor
|
|
Fluoroclebopride is a dopamine (DA) D2 receptor ligand. |
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T0990 |
Droperidol
|
NSC 169874,Dehydrobenzperidol |
Dopamine Receptor
|
|
Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist. |
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T38754 |
Trazpiroben
|
TAK-906 |
Dopamine Receptor
|
|
Trazpiroben (TAK-906) is a selective dopamine D2/D3 receptor antagonist used in the study of gastroparesis. |
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T6951 |
Pramipexole dihydrochloride hydrate
|
Pramipexole 2HCl Monohydrate,Mirapex |
Dopamine Receptor
|
|
Pramipexole dihydrochloride hydrate (Mirapex) is the hydrochloride salt of pramipexole, a benzothiazole derivative. As a nonergot dopamine agonist, pramipexole binds to D2 and D3 dopamine receptors in the striatum and su... |
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T2592 |
Ropinirole hydrochloride
|
SKF 101468 hydrochloride,SKF-101468A,Ropinirole HCl |
Dopamine Receptor
|
|
Ropinirole hydrochloride (SKF-101468A) is a selective dopamine D2 receptors agonist (Ki: 29 nM). Ropinirole hydrochloride (SKF-101468A) is the hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with anti... |
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T24613 |
PF-00217830
|
PF-217830 |
Dopamine Receptor
,
Serotonin Transporter
|
|
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizophrenia. |
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T14767 |
BP 897 hydrochloride
|
|
Dopamine Receptor
|
|
BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors ... |
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T3278 |
Piribedil
|
EU-4200,Trivastan,ET-495,Trivastal |
Dopamine Receptor
,
Histone Methyltransferase
,
Adrenergic Receptor
|
|
Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease. |
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T1201 |
Sulpiride
|
Aiglonyl,Dogmatil,Sulpyrid,Dolmatil,Dobren |
Dopamine Receptor
|
|
Sulpiride (Aiglonyl) is a dopamine D2-receptor antagonist, used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. |
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T28435 |
PNU-96391
|
PNU 96391,OSU6162,PNU96391,OSU 6162,OSU-6162 |
Dopamine Receptor
,
5-HT Receptor
|
|
PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases. |
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T2564 |
Cis-(Z)-Flupentixol dihydrochloride
|
Emergil,Flupenthixol dihydrochloride |
Dopamine Receptor
,
5-HT Receptor
|
|
cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist. |
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T1069 |
Metoclopramide hydrochloride
|
Maxolon,Metoclopramide HCl |
Dopamine Receptor
,
5-HT Receptor
,
AChR
|
|
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. |
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T4117 |
Zuclopenthixol
|
cis-Clopenthixol,Cisordinol,(Z)-Clopenthixol |
Dopamine Receptor
|
|
Zuclopenthixol (cis-Clopenthixol) is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. |
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T27677 |
JNJ-37822681
|
JNJ37822681,JNJ 37822681 |
Dopamine Receptor
|
|
JNJ-37822681 is a novel, highly selective dopamine D₂ receptor antagonist characterized by a rapid dissociation rate from the dopamine D₂ receptor. |
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T3431 |
Pardoprunox hydrochloride
|
SLV-308 hydrochloride,DU-126891 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
|
|
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A recept... |
|
T0351 |
Risperidone
|
Risperidal,R 64 766 |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
,
P-gp
|
|
Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent. |
|
T7352 |
Pridopidine
|
ACR16,ASP2314,FR310826 |
Dopamine Receptor
|
|
Pridopidine (FR310826), a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model. |
|
T21782 |
A 77636 hydrochloride
|
A77636 hydrochloride |
Dopamine Receptor
|
|
A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows antiparkinsonian activity. A 77636 hydrochloride is functionall... |
|
T9100 |
BP 897
|
2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- |
Dopamine Receptor
|
|
BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 ... |
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T10232 |
Acetophenazine dimaleate
|
|
Dopamine Receptor
|
|
Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor. |
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T28809 |
SLV-310
|
SLV 310,SLV310 |
Dopamine Receptor
,
5-HT Receptor
|
|
SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and schizophrenia. |
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T11079 |
NMI 8739
|
n-docosahexaenoyl dopamine,Dha-DA conjugate |
Dopamine Receptor
|
|
|
|
T26360 |
Benperidol
|
R4584,R-4584,Anquil,McN-JR-4584,R 4584 |
|
|
Benperidol (Anquil) is a butanone analog with antipsychotic and stabilizing properties, and has been shown to be effective in blocking D2 receptors.Benperidol can be used in positron emission tomography (PET) scanning to... |
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T5842 |
Bromocriptine mesylate
|
CB-154 |
Dopamine Receptor
,
Autophagy
|
|
Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM) |
|
T8385 |
Metoclopramide hydrochloride hydrate
|
Metoclopramide monohydrochloride monohydrate |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide hydrochloride hydrate (Metoclopramide monohydrochloride monohydrate) is a dopamine D2 antagonist that is a drug used for digestive dysfunction. It acts as an anti-emetic |
|
T28073 |
MLS1547
|
MLS000051547,MLS 1547,MLS-1547 |
Dopamine Receptor
|
|
MLS1547 (MLS000051547) is a highly efficacious agonist of G protein-biased dopamine D2 receptor with a Ki of 1.2 μM. MLS1547 stimulates D2R G protein-mediated signaling with EC50 of 0.37 μM in a calcium mobilization assa... |
|
T16472 |
Pericyazine
|
Propericiazine,RP 8909 |
Dopamine Receptor
|
|
Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe anxiety states and psych... |
|
T8389 |
Trifluoperazine
|
trifluoroperazine |
CaMK
,
Dopamine Receptor
,
Influenza Virus
,
Adrenergic Receptor
,
P-gp
,
Autophagy
|
|
Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia. |
|
T7553 |
(+)-PD 128907 hydrochloride
|
|
Dopamine Receptor
|
|
(+)-PD 128907 hydrochloride is an agonist of D3 dopamine receptor . |
